Simcere Pharmaceutical Group (Simcere Pharmaceutical) is a manufacturer and supplier of branded generic pharmaceuticals in the Chinese market. Its focus is to introduce generic and pharmaceutical products for the treatment of diseases with high incidence and/or mortality rate. The Company has introduced a generic anti-stroke medication under the brand name, Bicun, and an anti-cancer medication under the brand name, Endu. Its products include antibiotics, anti-stroke medications, anti-inflammatory drugs, anti-cancer medications and other medicines. In addition, it has obtained approvals from the China State Food and Drug Administration (SFDA) to manufacture and sell over 210 other products. In November 2007, the Company acquired Master Luck Corporation Limited, which holds 85.7% of Nanjing Tung Chit Pharmaceutical Co., Ltd. (Source: 20-F)
Aspen Pharmacare markets a broad range of ethical products. These products of original research include a number of well established brands. Aspen Pharmacare's ethical business is a leader in the categories of female healthcare, tranquillisers and hypnotics and cardiovascular medicines. A number of co-marketing agreements have been concluded with multinational companies in terms of which Aspen Pharmacare distributes leading ethical products. Aspen Pharmacare is the leading supplier of generic medicines to the private and public sectors. This leadership position has been achieved by the broad range of quality pharmaceuticals the Group is able to supply at affordable prices. The introduction of new legislation in South Africa compelling generic substitution is expected to lead to an increase in the use of generic medicines. The generic product range is the core of the Group's public sector business which is serviced by the supply of state tenders, public sector hospitals and parastatal institutions. Over the counter (OTC) products are marketed exclusively through pharmacies. Increasing trends in self-medication make this a focus area. Aspen Pharmacare has built particular strength in the niche natural product sector. Another area of emphasis is in lifestyle intervention products which provide a greater sense of "well-being" for users. The fast moving consumer goods (FMCG) division markets a number of well-known and trusted household brands, which are found on the shelves of hypermarkets, supermarkets and cash and carry outlets. Aspen Pharmacare has entered into an agreement with Tibbett and Britten ("T&B") for the provision of its total distribution requirements. It is expected that the change to T&B, one of the world's leaders in supply chain management, will lead to an improvement in efficiencies and resultant cost savings. There are two pharmaceutical manufacturing plants within Aspen Pharmacare. Aspen Pharmacare Lennon, based in Port Elizabeth, is the Group's flagship factory and the heart of its generic business. It manufactures over 20 tons of finished product daily. Aspen Pharmacare East London is the site of the Group's important penicillin plant as well as a specialised aerosol facility. An oral contraceptive facility has also been commissioned at the East London site during the course of the past financial year. This facility manufactures to international quality standards. The new business development ("NBD") unit is responsible for identifying and sourcing new products for Aspen Pharmacare to bring to the market. The Group's pharmaceutical research laboratories ("PRL") are focused on the core activity of developing products which are the first-to-market in the domestic generic sector. PRL has experience in formulating most dosage forms. The Aspen Pharmacare regulatory division has developed sophisticated systems to constantly monitor and prioritise update requirements at an individual product level. These systems also allow for detailed business management of this function in an effort to move staff away from the typical reactive approach and to focus them on the key business needs. This is essential for achieving success given Aspen Pharmacare's large product range. The regulatory department works closely in co-operation with the South African Medicines Control Council ("MCC") in bringing new product registrations to the market.
About PLIVA: With more than 80 years of experience in the pharmaceuticals arena, PLIVA has successfully transformed itself into a multinational corporation, with operations in CEE, the US and Western Europe. The company's vision is to be a research driven, fully integrated global pharmaceutical company dedicated to providing innovative products for a better quality of life. PLIVA is currently the largest CEE headquartered pharmaceutical company by sales, whose most prominent discovery is the blockbuster antibiotic azithromycin, sold under the trademarks of Zithromax and Sumamed.
Cipla Limited is a pharmaceutical company based in India. During the fiscal year ended March 31, 2007 (fiscal 2007), the Company launched many drugs and formulations, which include Ciclohale, which is a steroid inhaler for asthma prophylaxis; SimplyOne, which is a combination therapy for asthma prophylaxis; Neosurf, which is a rescue treatment for neonatal respiratory distress syndrome, and Elcepan, which is a combination therapy for epilepsy. The Company has alliances with nine generic majors including Teva Pharmaceuticals USA, Inc., Watson Pharmaceuticals, Inc., Eon Labs, Inc. and Akorn, Inc. for over 125 projects. It has entered into a research agreement with Avestha Gengraine Technologies Private Limited, to work on a collaborative biopharmaceuticals development programme. The Company has set up a wholly owned subsidiary Cipla FZE, in October 2006, at Jebel Ali Free Zone, Dubai, U.A.E. (Source: ARS)
Ranbaxy Laboratories Limited, India's largest pharmaceutical Company, manufactures and markets branded generic pharmaceuticals and Active Pharmaceutical Ingredients. Ranbaxy's continued focus on R&D has resulted in several approvals in developed markets and significant progress in New Drug Discovery Research.
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